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    CG15412 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33553, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG15412provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0031528
    Locus tag
    Dmel_CG15412
    See related
    AllianceGenome:FB:FBgn0031528
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG15412
    Summary
    Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to several human genes including FBXL17 (F-box and leucine rich repeat protein 17); FBXL18 (F-box and leucine rich repeat protein 18); and FBXL21P (F-box and leucine rich repeat protein 21, pseudogene). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG15412 in Genome Data Viewer
    Location:
    23F1-23F1; 2-10 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (3373567..3375711, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (3373567..3375711, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene GRAM domain containing 1B Neighboring gene uncharacterized protein Neighboring gene Phosphotyrosyl phosphatase activator

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    2. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235
    3. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG15412-PB
    CG15412-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      3373567..3375711 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001103602.2 → NP_001097072.1  uncharacterized protein Dmel_CG15412, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001097072.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V5G0, Q9VQP8
      Conserved Domains (2) summary
      cd09293
      Location:142 → 228
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:145 → 168
      LRR_AMN1; leucine-rich repeat [structural motif]

    2. NM_001273067.1 → NP_001259996.1  uncharacterized protein Dmel_CG15412, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259996.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PED9
      Conserved Domains (2) summary
      cd09293
      Location:142 → 228
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:145 → 168
      LRR_AMN1; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PED9 M9PED9
    Q4V5G0 Q4V5G0

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