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    Pop5 POP5 ribonuclease P/MRP subunit [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39915, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Pop5provided by FlyBase
    Official Full Name
    POP5 ribonuclease P/MRP subunitprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036696
    Locus tag
    Dmel_CG14057
    See related
    AllianceGenome:FB:FBgn0036696
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG14057; Dmel\CG14057
    Summary
    Predicted to enable ribonuclease P RNA binding activity. Predicted to be involved in rRNA processing and tRNA 5'-leader removal. Predicted to be part of nucleolar ribonuclease P complex and ribonuclease MRP complex. Orthologous to human POP5 (POP5 homolog, ribonuclease P/MRP subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Pop5 in Genome Data Viewer
    Location:
    73E5-73E5; 3-45 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17044401..17045038, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17037501..17038138, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43250 Neighboring gene bad egg Neighboring gene SR-related CTD associated factor 6 Neighboring gene PAPS transporter 2 Neighboring gene Troponin C at 73F Neighboring gene rogdi

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Biogenesis of RNase P RNA from an intron requires co-assembly with cognate protein subunits. Palsule G, et al. Nucleic Acids Res, 2019 Sep 19. PMID 31287870, Free PMC Article
    2. Inventory and analysis of the protein subunits of the ribonucleases P and MRP provides further evidence of homology between the yeast and human enzymes. Rosenblad MA, et al. Nucleic Acids Res, 2006. PMID 16998185, Free PMC Article
    3. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    4. Ultra-deep sequencing of ribosome-associated poly-adenylated RNA in early Drosophila embryos reveals hundreds of conserved translated sORFs. Li H, et al. DNA Res, 2016 Dec. PMID 27559081, Free PMC Article
    5. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ribonuclease P RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ribonuclease P RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in tRNA 5'-leader removal IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA 5'-leader removal ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in tRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in tRNA processing ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of multimeric ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of nucleolar ribonuclease P complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nucleolar ribonuclease P complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of ribonuclease MRP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonuclease MRP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of ribonuclease P complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    POP5 ribonuclease P/MRP subunit
    Names
    CG14057-PA
    CG14057-PB
    Pop5-PA
    Pop5-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17044401..17045038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140698.3 → NP_648955.1  POP5 ribonuclease P/MRP subunit, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648955.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4M5, Q9VVE0
      Related
      FBpp0075046
      Conserved Domains (1) summary
      pfam01900
      Location:7 → 111
      RNase_P_Rpp14; Rpp14/Pop5 family

    2. NM_001169987.1 → NP_001163458.1  POP5 ribonuclease P/MRP subunit, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001163458.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1JI31
      Conserved Domains (1) summary
      pfam01900
      Location:1 → 48
      RNase_P_Rpp14; Rpp14/Pop5 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    E1JI31 E1JI31
    Q9VVE0 Q9VVE0

    Gene LinkOut

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