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    Ir67c Ionotropic receptor 67c [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 317838, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ir67cprovided by FlyBase
    Official Full Name
    Ionotropic receptor 67cprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052058
    Locus tag
    Dmel_CG32058
    See related
    AllianceGenome:FB:FBgn0052058
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    67c; CG32058; DmelIR67c; Dmel\CG32058; IR67c
    Summary
    Predicted to enable ligand-gated monoatomic ion channel activity. Predicted to be involved in detection of chemical stimulus. Predicted to be located in membrane. Is expressed in chemosensory neuron of adult labral sensillum 7; labral sense organ neurons; and larval gustatory receptor neuron of the dorsal pharyngeal sense organ. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ir67c in Genome Data Viewer
    Location:
    67E3-67E3; 3-33 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (10432384..10434105, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (10425484..10427205, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ionotropic receptor 67b Neighboring gene Gemin 3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unpredictable Effects of the Genetic Background of Transgenic Lines in Physiological Quantitative Traits. Evangelou A, et al. G3 (Bethesda), 2019 Nov 5. PMID 31540975, Free PMC Article
    2. A receptor and neuron that activate a circuit limiting sucrose consumption. Joseph RM, et al. Elife, 2017 Mar 23. PMID 28332980, Free PMC Article
    3. Combinatorial Pharyngeal Taste Coding for Feeding Avoidance in Adult Drosophila. Chen YD, et al. Cell Rep, 2019 Oct 22. PMID 31644916, Free PMC Article
    4. Mitochondrial genomic variation drives differential nuclear gene expression in discrete regions of Drosophila gene and protein interaction networks. Mossman JA, et al. BMC Genomics, 2019 Sep 2. PMID 31477008, Free PMC Article
    5. Calcium Taste Avoidance in Drosophila. Lee Y, et al. Neuron, 2018 Jan 3. PMID 29276056, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ligand-gated monoatomic ion channel activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in detection of chemical stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ionotropic receptor 67c
    Names
    CG32058-PA
    Ir67c-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      10432384..10434105 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168407.1 → NP_729609.1  ionotropic receptor 67c [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729609.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQE2
      Related
      FBpp0076022, FBtr0076293
      Conserved Domains (1) summary
      pfam00060
      Location:288 → 500
      Lig_chan; Ligand-gated ion channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IQE2 Q8IQE2

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