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    CG9231 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40130, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG9231provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036887
    Locus tag
    Dmel_CG9231
    See related
    AllianceGenome:FB:FBgn0036887
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG9231
    Summary
    Predicted to be involved in cellular response to hypoxia; positive regulation of apoptotic process; and positive regulation of release of cytochrome c from mitochondria. Predicted to be located in cytosol and mitochondrion. Is expressed in adult head; adult heart; embryonic/larval midgut; gastric caecum; and organism. Orthologous to human FAM162A (family with sequence similarity 162 member A) and FAM162B (family with sequence similarity 162 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG9231 in Genome Data Viewer
    Location:
    76B8-76B8; 3-45 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (19585093..19586003, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (19578193..19579103, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45916 Neighboring gene mir-9a stem loop Neighboring gene Shaker cognate l Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene absent, small, or homeotic discs 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Microarray analysis of juvenile hormone response in Drosophila melanogaster S2 cells. Willis DK, et al. J Insect Sci, 2010. PMID 20672983, Free PMC Article
    2. Molecular genetic analysis of Chd3 and polytene chromosome region 76B-D in Drosophila melanogaster. Cooper MT, et al. Genetics, 2010 Jul. PMID 20439780, Free PMC Article
    3. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cellular response to hypoxia ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of release of cytochrome c from mitochondria ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG9231-PA
    CG9231-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      19585093..19586003 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300191.1 → NP_001287120.1  uncharacterized protein Dmel_CG9231, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287120.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VW12
      UniProtKB/TrEMBL
      X2JGV8
      Conserved Domains (1) summary
      pfam06388
      Location:29 → 110
      DUF1075; Protein of unknown function (DUF1075)

    2. NM_140871.3 → NP_649128.1  uncharacterized protein Dmel_CG9231, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649128.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VW12
      UniProtKB/TrEMBL
      X2JGV8
      Related
      FBpp0074740
      Conserved Domains (1) summary
      pfam06388
      Location:29 → 110
      DUF1075; Protein of unknown function (DUF1075)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VW12.1 Q9VW12
    X2JGV8 X2JGV8

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