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    CG4161 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34907, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4161provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028892
    Locus tag
    Dmel_CG4161
    See related
    AllianceGenome:FB:FBgn0028892
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BG:DS03023.2; Dmel\CG4161
    Summary
    Predicted to enable phosphatase activity. Predicted to be involved in DNA damage response. Orthologous to human ARMT1 (acidic residue methyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4161 in Genome Data Viewer
    Location:
    35D2-35D2; 2-51 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15433309..15435304)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15433309..15435304)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene worniu Neighboring gene long non-coding RNA:CR44861 Neighboring gene long non-coding RNA:CR44862

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Germ line-inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition. Zenk F, et al. Science, 2017 Jul 14. PMID 28706074
    2. Wake-up-call, a lin-52 paralogue, and Always early, a lin-9 homologue physically interact, but have opposing functions in regulating testis-specific gene expression. Doggett K, et al. Dev Biol, 2011 Jul 15. PMID 21570388, Free PMC Article
    3. An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster: the Adh region. Ashburner M, et al. Genetics, 1999 Sep. PMID 10471707, Free PMC Article
    4. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article
    5. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA damage response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4161-PA
    CG4161-PB
    NP_001285955.1
    NP_609753.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15433309..15435304
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299026.1 → NP_001285955.1  uncharacterized protein Dmel_CG4161, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285955.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ77, Q9V3Z7
      Conserved Domains (1) summary
      pfam01937
      Location:40 → 426
      DUF89; Protein of unknown function DUF89

    2. NM_135909.3 → NP_609753.1  uncharacterized protein Dmel_CG4161, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_609753.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MZ77, Q9V3Z7
      Related
      FBpp0080294
      Conserved Domains (1) summary
      pfam01937
      Location:40 → 426
      DUF89; Protein of unknown function DUF89
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MZ77 Q8MZ77
    Q9V3Z7 Q9V3Z7

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