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    Tektin-A Tektin A [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34934, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tektin-Aprovided by FlyBase
    Official Full Name
    Tektin Aprovided by FlyBase
    Primary source
    FLYBASE:FBgn0028902
    Locus tag
    Dmel_CG4767
    See related
    AllianceGenome:FB:FBgn0028902
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.235; BG:DS02252.2; CG4767; Dmel\CG4767
    Summary
    Predicted to be involved in cilium assembly and cilium movement involved in cell motility. Predicted to be active in microtubule cytoskeleton. Is expressed in several structures, including adult head; chordotonal organ precursor cell; embryonic head sensory system; male germline cell; and sensory nervous system primordium. Orthologous to human TEKT4 (tektin 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Tektin-A in Genome Data Viewer
    Location:
    35D5-35D5; 2-51 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (15854126..15856450)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (15854126..15856450)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43763 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR42791 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Forkhead transcription factor Fd3F cooperates with Rfx to regulate a gene expression program for mechanosensory cilia specialization. Newton FG, et al. Dev Cell, 2012 Jun 12. PMID 22698283, Free PMC Article
    2. Neighbourhood continuity is not required for correct testis gene expression in Drosophila. Meadows LA, et al. PLoS Biol, 2010 Nov 30. PMID 21151342, Free PMC Article
    3. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    4. Proteome mapping of the Drosophila melanogaster male reproductive system. Takemori N, et al. Proteomics, 2009 May. PMID 19343724
    5. Individual histone deacetylases in Drosophila modulate transcription of distinct genes. Cho Y, et al. Genomics, 2005 Nov. PMID 16137856

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium movement involved in cell motility IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cilium movement involved in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    tektin A
    Names
    CG4767-PA
    CG4767-PB
    TEKTIN A
    Tektin-A-PA
    Tektin-A-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      15854126..15856450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001273547.1 → NP_001260476.1  tektin A, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260476.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3M9
      Conserved Domains (1) summary
      pfam03148
      Location:192 → 571
      Tektin; Tektin family

    2. NM_078853.3 → NP_523577.1  tektin A, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523577.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9V3M9
      Related
      FBpp0080346
      Conserved Domains (1) summary
      pfam03148
      Location:192 → 571
      Tektin; Tektin family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9V3M9 Q9V3M9

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