uso1 USO1 vesicle transport factor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: uso1provided by ZNC
Official Full Name: USO1 vesicle transport factorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-688
See related: Ensembl:ENSDARG00000019581 AllianceGenome:ZFIN:ZDB-GENE-040426-688
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: vdp; zgc:55298
Summary: Predicted to be involved in several processes, including Golgi vesicle transport; intracellular protein transport; and transcytosis. Predicted to act upstream of or within vesicle fusion with Golgi apparatus. Predicted to be located in Golgi membrane. Predicted to be active in ER to Golgi transport vesicle membrane; Golgi stack; and endoplasmic reticulum. Is expressed in notochord. Orthologous to human USO1 (USO1 vesicle transport factor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 26

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (26467071..26508138)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (25773337..25814422)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

fi05d03.x1 (e-PCR)
- UniSTS:196673

fc13a12.y1 (e-PCR)
- UniSTS:192611

fc73f03.x1 (e-PCR)
- UniSTS:194403

fc73f08.x1 (e-PCR)
- UniSTS:194405

Z6415 (e-PCR)
- UniSTS:80793

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in Golgi vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in animal organ development	IEA Inferred from Electronic Annotation more info
involved_in endoplasmic reticulum to Golgi vesicle-mediated transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within intracellular protein transport	IEA Inferred from Electronic Annotation more info
involved_in membrane fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in transcytosis	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within vesicle fusion with Golgi apparatus	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in ER to Golgi transport vesicle membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
is_active_in Golgi stack	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: general vesicular transport factor p115

Names: USO1 homolog, vesicle docking protein; vesicle docking protein p115

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200155.1 → NP_956449.1 general vesicular transport factor p115

See identical proteins and their annotated locations for NP_956449.1

Status: PROVISIONAL

Source sequence(s)

BC045300

UniProtKB/TrEMBL

B2GSX0, Q7ZW40

Related

ENSDARP00000101948.4, ENSDART00000112329.6

Conserved Domains (4) summary

COG1340
Location:648 → 934

COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]

pfam04869
Location:351 → 637

Uso1_p115_head; Uso1 / p115 like vesicle tethering protein, head region

pfam04871
Location:831 → 932

Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region

pfam07106
Location:736 → 818

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

26467071..26508138

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009291483.4 → XP_009289758.1 general vesicular transport factor p115 isoform X2

UniProtKB/TrEMBL

A0A2R8QLN9, A0A8M3ASH2

Related

ENSDARP00000153932.1, ENSDART00000193833.1

Conserved Domains (4) summary

COG1340
Location:641 → 927

COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]

pfam04869
Location:351 → 630

Uso1_p115_head; Uso1 / p115 like vesicle tethering protein, head region

pfam04871
Location:824 → 925

Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region

pfam07106
Location:729 → 811

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
XM_009291480.4 → XP_009289755.1 general vesicular transport factor p115 isoform X1

UniProtKB/TrEMBL

A0A8M3AIA6, E7F2J5

Related

ENSDARP00000015515.7, ENSDART00000011809.7

Conserved Domains (4) summary

COG1340
Location:644 → 930

COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]

pfam04869
Location:347 → 633

Uso1_p115_head; Uso1 / p115 like vesicle tethering protein, head region

pfam04871
Location:827 → 928

Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region

pfam07106
Location:732 → 814

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
XM_009291485.4 → XP_009289760.1 general vesicular transport factor p115 isoform X3

UniProtKB/TrEMBL

A0A8M3APK5

Conserved Domains (4) summary

COG1340
Location:637 → 923

COG1340; Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]

pfam04869
Location:347 → 626

Uso1_p115_head; Uso1 / p115 like vesicle tethering protein, head region

pfam04871
Location:820 → 921

Uso1_p115_C; Uso1 / p115 like vesicle tethering protein, C terminal region

pfam07106
Location:725 → 807

TBPIP; Tat binding protein 1(TBP-1)-interacting protein (TBPIP)