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    trip10a thyroid hormone receptor interactor 10a [ Danio rerio (zebrafish) ]

    Gene ID: 492762, updated on 9-Dec-2024

    Summary

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    Official Symbol
    trip10aprovided by ZNC
    Official Full Name
    thyroid hormone receptor interactor 10aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-105
    See related
    Ensembl:ENSDARG00000005679 AllianceGenome:ZFIN:ZDB-GENE-041114-105
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    trip10; zgc:101777
    Summary
    Predicted to enable lipid binding activity. Predicted to act upstream of or within endocytosis and signal transduction. Predicted to be located in several cellular components, including cell cortex; cytoskeleton; and lysosome. Is expressed in blastodisc. Orthologous to human TRIP10 (thyroid hormone receptor interactor 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See trip10a in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (54434205..54500301, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (54179542..54245670, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene olfactomedin 2a Neighboring gene uncharacterized LOC137490169 Neighboring gene si:ch73-208g10.1 Neighboring gene angiopoietin-like 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The regulation of transcriptome responses in zebrafish embryo exposure to triadimefon. Hsu LS, et al. Environ Toxicol, 2017 Jan. PMID 26790661
    2. Genome wide analysis of 3' UTR sequence elements and proteins regulating mRNA stability during maternal-to-zygotic transition in zebrafish. Vejnar CE, et al. Genome Res, 2019 Jul. PMID 31227602, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell cortex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cdc42-interacting protein 4 homolog
    Names
    thyroid receptor-interacting protein 10 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007403.1 → NP_001007404.1  cdc42-interacting protein 4 homolog

      See identical proteins and their annotated locations for NP_001007404.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085435
      UniProtKB/Swiss-Prot
      Q5U3Q6
      UniProtKB/TrEMBL
      B2GT06
      Conserved Domains (3) summary
      cd07653
      Location:5 → 257
      F-BAR_CIP4-like; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Cdc42-Interacting Protein 4 and similar proteins
      cd11628
      Location:342 → 422
      HR1_CIP4_FNBP1L; Protein kinase C-related kinase homology region 1 (HR1) Rho-binding domain of vertebrate Cdc42-Interacting Protein 4 and FormiN Binding Protein 1-Like
      cd11911
      Location:484 → 538
      SH3_CIP4-like; Src Homology 3 domain of Cdc42-Interacting Protein 4

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      54434205..54500301 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017354077.3 → XP_017209566.1  cdc42-interacting protein 4 homolog isoform X2

      UniProtKB/TrEMBL
      A0A8M6YWI7, E7FFS0
      Related
      ENSDARP00000105597.3, ENSDART00000124215.3

    2. XM_017354074.3 → XP_017209563.1  cdc42-interacting protein 4 homolog isoform X1

      UniProtKB/TrEMBL
      A0A8M6YVX4
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5U3Q6.1 GenPept UniProtKB/Swiss-Prot:Q5U3Q6

    Gene LinkOut

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