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    ggctb gamma-glutamylcyclotransferase b [ Danio rerio (zebrafish) ]

    Gene ID: 406278, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ggctbprovided by ZNC
    Official Full Name
    gamma-glutamylcyclotransferase bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1939
    See related
    Ensembl:ENSDARG00000005085 AllianceGenome:ZFIN:ZDB-GENE-040426-1939
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ggct; fj35c05; zgc:56140; wu:fj35b07; wu:fj35c05
    Summary
    Predicted to enable gamma-glutamylcyclotransferase activity. Is expressed in chondrocranium; lens; retina; and somite. Orthologous to human GGCT (gamma-glutamylcyclotransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ggctb in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (53686410..53708501)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (54000913..54023004)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene mucin-21 Neighboring gene uncharacterized LOC137487994 Neighboring gene nucleotide-binding oligomerization domain containing 1 Neighboring gene zinc and ring finger 2b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Structure and expression pattern of teleost caspase recruitment domain (CARD) containing proteins that are potentially involved in NF-kappaB signalling. Chang MX, et al. Dev Comp Immunol, 2010 Jan. PMID 19699229
    2. Gene expression analysis of zebrafish melanocytes, iridophores, and retinal pigmented epithelium reveals indicators of biological function and developmental origin. Higdon CW, et al. PLoS One, 2013. PMID 23874447, Free PMC Article
    3. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables gamma-glutamylcyclotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables gamma-glutamylcyclotransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    gamma-glutamylcyclotransferase
    Names
    gamma-glutamyl cyclotransferase b
    NP_998170.1
    XP_005173601.1
    XP_021322344.1
    XP_021322345.1
    XP_068070027.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213005.1 → NP_998170.1  gamma-glutamylcyclotransferase precursor

      See identical proteins and their annotated locations for NP_998170.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045940
      UniProtKB/TrEMBL
      Q7ZVA5
      Related
      ENSDARP00000026224.9, ENSDART00000014098.11
      Conserved Domains (2) summary
      COG3703
      Location:36 → 213
      ChaC; Cation transport regulator ChaC [Inorganic ion transport and metabolism]
      pfam13772
      Location:104 → 184
      AIG2_2; AIG2-like family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      53686410..53708501
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005173544.4 → XP_005173601.1  gamma-glutamylcyclotransferase isoform X1

      UniProtKB/TrEMBL
      A0A8M2BKT7
      Conserved Domains (2) summary
      COG3703
      Location:18 → 195
      ChaC; Cation transport regulator ChaC [Inorganic ion transport and metabolism]
      pfam13772
      Location:86 → 166
      AIG2_2; AIG2-like family

    2. XM_068213926.1 → XP_068070027.1  gamma-glutamylcyclotransferase isoform X2

      UniProtKB/TrEMBL
      A0A8M9PD19

    3. XM_021466669.2 → XP_021322344.1  gamma-glutamylcyclotransferase isoform X2

      UniProtKB/TrEMBL
      A0A8M9PD19
      Conserved Domains (2) summary
      COG3703
      Location:7 → 184
      ChaC; Cation transport regulator ChaC [Inorganic ion transport and metabolism]
      pfam13772
      Location:75 → 155
      AIG2_2; AIG2-like family

    4. XM_021466670.1 → XP_021322345.1  gamma-glutamylcyclotransferase isoform X2

      UniProtKB/TrEMBL
      A0A8M9PD19
      Conserved Domains (2) summary
      COG3703
      Location:7 → 184
      ChaC; Cation transport regulator ChaC [Inorganic ion transport and metabolism]
      pfam13772
      Location:75 → 155
      AIG2_2; AIG2-like family
    Nucleotide Protein
    Heading Accession and Version

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