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    snrpb small nuclear ribonucleoprotein polypeptides B and B1 [ Danio rerio (zebrafish) ]

    Gene ID: 402966, updated on 4-Jan-2025

    Summary

    Official Symbol
    snrpbprovided by ZNC
    Official Full Name
    small nuclear ribonucleoprotein polypeptides B and B1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1819
    See related
    Ensembl:ENSDARG00000011125 AllianceGenome:ZFIN:ZDB-GENE-040426-1819
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    Snrpn; zgc:77315
    Summary
    Predicted to enable snRNP binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex and spliceosomal snRNP complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Prader-Willi syndrome; cerebrocostomandibular syndrome; and mixed connective tissue disease. Orthologous to human SNURF (SNRPN upstream open reading frame); SNRPN (small nuclear ribonucleoprotein polypeptide N); and SNRPB (small nuclear ribonucleoprotein polypeptides B and B1). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
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    Genomic context

    See snrpb in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (57478337..57485411, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (57481473..57488547, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene zinc finger, NFX1-type containing 1 Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 Neighboring gene itchy E3 ubiquitin protein ligase a Neighboring gene N-terminal EF-hand calcium binding protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC77315

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables snRNP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type prespliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U4 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U5 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    small nuclear ribonucleoprotein-associated proteins B and B'
    Names
    snRNP-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205667.1NP_991230.1  small nuclear ribonucleoprotein-associated proteins B and B'

      See identical proteins and their annotated locations for NP_991230.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065601
      UniProtKB/TrEMBL
      Q6P0I9, Q9I9E5
      Related
      ENSDARP00000023337.7, ENSDART00000011663.9
      Conserved Domains (1) summary
      cd01717
      Location:583
      Sm_B; Sm protein B

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      57478337..57485411 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)