ctbs chitobiase, di-N-acetyl- [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ctbsprovided by ZNC
Official Full Name: chitobiase, di-N-acetyl-provided by ZNC
Primary source: ZFIN:ZDB-GENE-050522-422
See related: Ensembl:ENSDARG00000100002 AllianceGenome:ZFIN:ZDB-GENE-050522-422
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:91983; zgc:109937
Summary: Predicted to enable chitin binding activity and hydrolase activity, hydrolyzing O-glycosyl compounds. Predicted to be involved in oligosaccharide catabolic process. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in lysosome. Is expressed in yolk syncytial layer. Orthologous to human CTBS (chitobiase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (16070436..16083610)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (15935803..15948975)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables chitin binding	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, acting on glycosyl bonds	IEA Inferred from Electronic Annotation more info
enables hydrolase activity, hydrolyzing O-glycosyl compounds	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in oligosaccharide catabolic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
located_in lysosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: di-N-acetylchitobiase

NP_001018565.1

EC 3.2.1.-

XP_068080271.1

EC 3.2.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001020729.1 → NP_001018565.1 di-N-acetylchitobiase precursor

See identical proteins and their annotated locations for NP_001018565.1

Status: PROVISIONAL

Source sequence(s)

BC095064

UniProtKB/TrEMBL

Q504D9

Related

ENSDARP00000133086.1, ENSDART00000162972.3

Conserved Domains (2) summary

cd02875
Location:5 → 358

GH18_chitobiase; Chitobiase (also known as di-N-acetylchitobiase) is a lysosomal glycosidase that hydrolyzes the reducing-end N-acetylglucosamine from the chitobiose core of oligosaccharides during the ordered degradation of asparagine-linked glycoproteins in eukaryotes. ...

smart00636
Location:95 → 334

Glyco_18; Glyco_18 domain