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    cldn23.1 claudin 23.1 [ Danio rerio (zebrafish) ]

    Gene ID: 553515, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cldn23.1provided by ZNC
    Official Full Name
    claudin 23.1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-091204-28
    See related
    Ensembl:ENSDARG00000028096 AllianceGenome:ZFIN:ZDB-GENE-091204-28
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cldn23a; cldn23a2; si:ch211-95j8.2
    Summary
    Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be located in anchoring junction and membrane. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN23 (claudin 23). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See cldn23.1 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 10 NC_007121.7 (15046837..15048788, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 10 NC_007121.6 (15088718..15090709, complement)

    Chromosome 10 - NC_007121.7Genomic Context describing neighboring genes Neighboring gene si:dkey-88l16.5 Neighboring gene uncharacterized LOC100537265 Neighboring gene claudin 23.2 Neighboring gene prostate androgen-regulated mucin-like protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Meta-Analysis of Grainyhead-Like Dependent Transcriptional Networks: A Roadmap for Identifying Novel Conserved Genetic Pathways. Mathiyalagan N, et al. Genes (Basel), 2019 Oct 31. PMID 31683705, Free PMC Article
    2. Phylogenetic revision of the claudin gene family. Baltzegar DA, et al. Mar Genomics, 2013 Sep. PMID 23726886
    3. What makes a bad egg? Egg transcriptome reveals dysregulation of translational machinery and novel fertility genes important for fertilization. Cheung CT, et al. BMC Genomics, 2019 Jul 15. PMID 31307377, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in bicellular tight junction assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in anchoring junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in bicellular tight junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in bicellular tight junction IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    claudin 23a
    Names
    claudin 23

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001386714.1 → NP_001373643.1  claudin 23a precursor

      Status: VALIDATED

      Source sequence(s)
      CR536613, CT027832
      UniProtKB/TrEMBL
      A0A8M1Q785, F1Q6Q0
      Related
      ENSDARP00000030329.4, ENSDART00000038401.5
      Conserved Domains (1) summary
      cl21598
      Location:5 → 179
      PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007121.7 Reference GRCz11 Primary Assembly

      Range
      15046837..15048788 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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