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    rbm46 RNA binding motif protein 46 [ Danio rerio (zebrafish) ]

    Gene ID: 566042, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rbm46provided by ZNC
    Official Full Name
    RNA binding motif protein 46provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061013-298
    See related
    Ensembl:ENSDARG00000079452 AllianceGenome:ZFIN:ZDB-GENE-061013-298
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fe11d09; wu:fe11d09; zgc:153695
    Summary
    Predicted to enable mRNA binding activity. Predicted to act upstream of or within meiotic cell cycle; oogenesis; and spermatogenesis. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human RBM46 (RNA binding motif protein 46). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rbm46 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (10127209..10137452)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (9443098..9453341)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene lecithin retinol acyltransferase-like Neighboring gene lecithin retinol acyltransferase b, tandem duplicate 2 Neighboring gene neuropeptide Y receptor Y2, like Neighboring gene uncharacterized LOC137495431

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Rbm46, a novel germ cell-specific factor, modulates meiotic progression and spermatogenesis. Dai X, et al. Biol Reprod, 2021 May 7. PMID 33524105
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Rbm46, a novel germ cell-specific factor, modulates meiotic progression and spermatogenesis.
      Title: Rbm46, a novel germ cell-specific factor, modulates meiotic progression and spermatogenesis.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within oogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    probable RNA-binding protein 46

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080024.2 → NP_001073493.2  probable RNA-binding protein 46

      Status: PROVISIONAL

      Source sequence(s)
      BC124720
      UniProtKB/Swiss-Prot
      Q08BH5
      Related
      ENSDARP00000099341.2, ENSDART00000110698.5
      Conserved Domains (4) summary
      cd12484
      Location:58 → 134
      RRM1_RBM46; RNA recognition motif 1 found in vertebrate RNA-binding protein 46 (RBM46)
      cd12492
      Location:136 → 220
      RRM2_RBM46; RNA recognition motif 2 found in vertebrate RNA-binding protein 46 (RBM46)
      pfam14709
      Location:392 → 463
      DND1_DSRM; double strand RNA binding domain from DEAD END PROTEIN 1
      cl17169
      Location:225 → 305
      RRM_SF; RNA recognition motif (RRM) superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      10127209..10137452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08BH5.1 GenPept UniProtKB/Swiss-Prot:Q08BH5

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