eif3eb eukaryotic translation initiation factor 3, subunit E, b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: eif3ebprovided by ZNC
Official Full Name: eukaryotic translation initiation factor 3, subunit E, bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050208-283
See related: Ensembl:ENSDARG00000002549 AllianceGenome:ZFIN:ZDB-GENE-050208-283
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: eif3s6b; im:7147439
Summary: Predicted to contribute to translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex. Predicted to be active in nucleus. Orthologous to human EIF3E (eukaryotic translation initiation factor 3 subunit E). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (22624269..22664128, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (23039946..23079831, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc05a04.y1 (e-PCR)
- UniSTS:192188

fc15e04.x1 (e-PCR)
- UniSTS:192734

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables translation initiation factor activity	IEA Inferred from Electronic Annotation more info
contributes_to translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in formation of cytoplasmic translation initiation complex	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within translational initiation	IEA Inferred from Electronic Annotation more info
involved_in translational initiation	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of eukaryotic 43S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic 48S preinitiation complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 3 complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	ISS Inferred from Sequence or Structural Similarity more info
part_of eukaryotic translation initiation factor 3 complex, eIF3e	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: eukaryotic translation initiation factor 3 subunit E-B

Names: eukaryotic translation initiation factor 3, subunit 6b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001362621.1 → NP_001349550.1 eukaryotic translation initiation factor 3 subunit E-B

Status: VALIDATED

Source sequence(s)

BX957242

UniProtKB/Swiss-Prot

Q1LUA7, Q1LUA8

UniProtKB/TrEMBL

A0A8M2BHD7, F1QHS3

Related

ENSDARP00000003276.8, ENSDART00000023926.11

Conserved Domains (2) summary

pfam01399
Location:291 → 395

PCI; PCI domain

pfam09440
Location:5 → 138

eIF3_N; eIF3 subunit 6 N terminal domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007130.7 Reference GRCz11 Primary Assembly

Range

22624269..22664128 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001044951.1: Suppressed sequence

Description

NM_001044951.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.