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    metrn meteorin, glial cell differentiation regulator [ Danio rerio (zebrafish) ]

    Gene ID: 494493, updated on 9-Dec-2024

    Summary

    Official Symbol
    metrnprovided by ZNC
    Official Full Name
    meteorin, glial cell differentiation regulatorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050102-1
    See related
    Ensembl:ENSDARG00000030367 AllianceGenome:ZFIN:ZDB-GENE-050102-1
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    mtrn; zgc:92132; wu:fb81a08
    Summary
    Predicted to enable hormone activity. Acts upstream of or within neural crest-derived cardiac glial cell differentiation. Predicted to be active in extracellular space. Is expressed in several structures, including blastomere; heart; neural plate; retina; and tail bud. Orthologous to human METRN (meteorin, glial cell differentiation regulator). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See metrn in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (37941614..37955994, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (38053717..38068097, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene dynein light chain Tctex-type protein 2B-like Neighboring gene coiled-coil domain containing 78 Neighboring gene uncharacterized LOC137489271 Neighboring gene proline rich 35 Neighboring gene C-reactive protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables hormone activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in glial cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within neural crest-derived cardiac glial cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of axonogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009983.2NP_001009983.2  meteorin precursor

      Status: VALIDATED

      Source sequence(s)
      BX294095
      UniProtKB/TrEMBL
      A0A8M1N3X3, F1QJ72
      Related
      ENSDARP00000041804.5, ENSDART00000041805.6

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      37941614..37955994 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395184.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      225274..240265 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395368.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      66014..80919 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)