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    lasp1 LIM and SH3 protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 323216, updated on 9-Dec-2024

    Summary

    Official Symbol
    lasp1provided by ZNC
    Official Full Name
    LIM and SH3 protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1936
    See related
    Ensembl:ENSDARG00000057867 AllianceGenome:ZFIN:ZDB-GENE-030131-1936
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb92f05; zgc:77542; wu:fb92f05
    Summary
    Predicted to enable actin filament binding activity. Predicted to act upstream of or within monoatomic ion transport. Predicted to be located in cell cortex and cytoskeleton. Predicted to be active in focal adhesion. Is expressed in brain; digestive system; eye; muscle; and trunk. Orthologous to human LASP1 (LIM and SH3 protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See lasp1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (16072972..16109815, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (15923172..15960015, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene si:dkey-81l17.6 Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene transfer RNA cysteine (anticodon GCA) Neighboring gene transfer RNA cysteine (anticodon GCA)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables actin filament binding  
    enables metal ion binding  
    Component Evidence Code Pubs
    located_in cell cortex  
    located_in cytoplasm  
    located_in cytoskeleton  
    is_active_in focal adhesion  

    General protein information

    Preferred Names
    LIM and SH3 domain protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212636.1 → NP_997801.1  LIM and SH3 domain protein 1

      See identical proteins and their annotated locations for NP_997801.1

      Status: PROVISIONAL

      Source sequence(s)
      BC066574
      UniProtKB/TrEMBL
      A9JT31, F6P5I6, Q6NYJ1
      Related
      ENSDARP00000051806.4, ENSDART00000051807.6
      Conserved Domains (3) summary
      smart00227
      Location:98 → 128
      NEBU; The Nebulin repeat is present also in Las1
      cd09447
      Location:5 → 57
      LIM_LASP; The LIM domain of LIM and SH3 Protein (LASP)
      cd11934
      Location:176 → 234
      SH3_Lasp1_C; C-terminal Src Homology 3 domain of LIM and SH3 domain protein 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      16072972..16109815 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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