cyb5r1 cytochrome b5 reductase 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cyb5r1provided by ZNC
Official Full Name: cytochrome b5 reductase 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8497
See related: Ensembl:ENSDARG00000018966 AllianceGenome:ZFIN:ZDB-GENE-030131-8497
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: dia1; zgc:56042; wu:fb13e02; wu:fb15h03
Summary: Predicted to enable FAD binding activity. Predicted to be located in membrane. Predicted to be active in mitochondrion. Orthologous to human CYB5R1 (cytochrome b5 reductase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 11

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	11	NC_007122.7 (24786418..24799675)
105	previous assembly	GRCz10 (GCF_000002035.5)	11	NC_007122.6 (24548802..24562059)

Chromosome 11 - NC_007122.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AI396849 (e-PCR)
- UniSTS:206687

fb13e02.x1 (e-PCR)
- UniSTS:202897

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables FAD binding	IBA Inferred from Biological aspect of Ancestor more info
enables cytochrome-b5 reductase activity, acting on NAD(P)H	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: NADH-cytochrome b5 reductase 1

Names: diaphorase (NADH) (cytochrome b-5 reductase)

NP_956483.1

EC 1.6.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200189.2 → NP_956483.1 NADH-cytochrome b5 reductase 1

See identical proteins and their annotated locations for NP_956483.1

Status: PROVISIONAL

Source sequence(s)

AY398332

UniProtKB/TrEMBL

Q7ZVF8

Related

ENSDARP00000003519.5, ENSDART00000015374.6

Conserved Domains (2) summary

cd06183
Location:48 → 304

cyt_b5_reduct_like; Cytochrome b5 reductase catalyzes the reduction of 2 molecules of cytochrome b5 using NADH as an electron donor. Like ferredoxin reductases, these proteins have an N-terminal FAD binding subdomain and a C-terminal NADH binding subdomain, separated by a ...

PTZ00319
Location:26 → 304

PTZ00319; NADH-cytochrome B5 reductase; Provisional