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    ube2q2 ubiquitin-conjugating enzyme E2Q family member 2 [ Danio rerio (zebrafish) ]

    Gene ID: 406260, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ube2q2provided by ZNC
    Official Full Name
    ubiquitin-conjugating enzyme E2Q family member 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1919
    See related
    Ensembl:ENSDARG00000013990 AllianceGenome:ZFIN:ZDB-GENE-040426-1919
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56219; wu:fi34a03
    Summary
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein polyubiquitination. Predicted to be active in nucleus. Orthologous to human UBE2Q2 (ubiquitin conjugating enzyme E2 Q2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See ube2q2 in Genome Data Viewer
    Location:
    chromosome: 25
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (29427852..29463878, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (28984845..29020871, complement)

    Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A5 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A4 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A3 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A2 Neighboring gene UDP glucuronosyltransferase 5 family, polypeptide A1 Neighboring gene interleukin 17 receptor E-like Neighboring gene kelch repeat and BTB domain containing 13b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin conjugating enzyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein polyubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin-conjugating enzyme E2 Q2
    NP_001315128.1
    NP_001315130.1
    NP_001315132.1
    NP_001315133.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001328199.1 → NP_001315128.1  ubiquitin-conjugating enzyme E2 Q2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      CU179703, CU469568
      UniProtKB/TrEMBL
      A0A8M1P4I9, A0A8M9PA27, X1WFM4
      Related
      ENSDARP00000129028.1, ENSDART00000155676.3

    2. NM_001328201.1 → NP_001315130.1  ubiquitin-conjugating enzyme E2 Q2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU179703, CU469568
      UniProtKB/TrEMBL
      A0A8M1P3M6, A0A8M9PA27, E7F1U7
      Related
      ENSDARP00000109060.2, ENSDART00000124645.3

    3. NM_001328203.1 → NP_001315132.1  ubiquitin-conjugating enzyme E2 Q2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      CU179703, CU469568
      UniProtKB/TrEMBL
      A0A2R8QLP1, A0A8M1P8W9, A0A8M9PFF6
      Related
      ENSDARP00000153455.1, ENSDART00000192593.1

    4. NM_001328204.1 → NP_001315133.1  ubiquitin-conjugating enzyme E2 Q2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      CU179703, CU469568
      UniProtKB/TrEMBL
      A0A2R8Q670, A0A8M1P4J4, A0A8M9PFF6
      Related
      ENSDARP00000149600.1, ENSDART00000181055.1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007136.7 Reference GRCz11 Primary Assembly

      Range
      29427852..29463878 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_212987.1: Suppressed sequence

      Description
      NM_212987.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein Strain
    Heading Accession and Version

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