alpi.2 alkaline phosphatase, intestinal, tandem duplicate 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: alpi.2provided by ZNC
Official Full Name: alkaline phosphatase, intestinal, tandem duplicate 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-050626-142
See related: Ensembl:ENSDARG00000053774 AllianceGenome:ZFIN:ZDB-GENE-050626-142
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fb68b10; wu:fb68b10; zgc:110409; si:ch211-262h13.2
Summary: Predicted to enable alkaline phosphatase activity. Predicted to be located in side of membrane. Predicted to be active in plasma membrane. Is expressed in intestinal bulb; intestine; and yolk syncytial layer. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to several human genes including ALPI (alkaline phosphatase, intestinal). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (38778858..38792815)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (38791904..38806071)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fa95f04.x1 (e-PCR)
- UniSTS:202599

fd48f05.y1 (e-PCR)
- UniSTS:195527

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables alkaline phosphatase activity	IBA Inferred from Biological aspect of Ancestor more info
enables alkaline phosphatase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in side of membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: intestinal-type alkaline phosphatase

Names: alkaline phosphatase, intestinal.2; intestinal alkaline phosphatase 2

NP_001020359.1

EC 3.1.3.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.