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    tsr3 TSR3 ribosome maturation factor [ Danio rerio (zebrafish) ]

    Gene ID: 436643, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tsr3provided by ZNC
    Official Full Name
    TSR3 ribosome maturation factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-63
    See related
    Ensembl:ENSDARG00000038567 AllianceGenome:ZFIN:ZDB-GENE-040718-63
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:92086
    Summary
    Predicted to enable 18S rRNA aminocarboxypropyltransferase activity and S-adenosyl-L-methionine binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within rRNA processing. Predicted to be located in cytoplasm. Orthologous to human TSR3 (TSR3 ribosome maturation factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tsr3 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (37329119..37337973, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (37441399..37450253, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene potassium channel tetramerization domain containing 5b Neighboring gene 3-phosphoinositide dependent protein kinase 1b Neighboring gene N-acetylglucosamine-1-phosphate transferase subunit gamma Neighboring gene SH3 domain binding kinase 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables 18S rRNA aminocarboxypropyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables S-adenosyl-L-methionine binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity, transferring alkyl or aryl (other than methyl) groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in enzyme-directed rRNA pseudouridine synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    18S rRNA aminocarboxypropyltransferase
    Names
    TSR3, 20S rRNA accumulation, homolog
    TSR3, acp transferase ribosome maturation factor
    NP_001002370.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002370.1 → NP_001002370.1  18S rRNA aminocarboxypropyltransferase

      See identical proteins and their annotated locations for NP_001002370.1

      Status: PROVISIONAL

      Source sequence(s)
      BC075886
      UniProtKB/TrEMBL
      Q6DHT1
      Related
      ENSDARP00000056302.5, ENSDART00000056303.7
      Conserved Domains (3) summary
      COG2042
      Location:54 → 221
      Tsr3; Ribosome biogenesis protein Tsr3 (rRNA maturation) [Translation, ribosomal structure and biogenesis]
      pfam04034
      Location:95 → 219
      DUF367; Domain of unknown function (DUF367)
      pfam04068
      Location:58 → 91
      RLI; Possible Fer4-like domain in RNase L inhibitor, RLI

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      37329119..37337973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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