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    pwwp2b PWWP domain containing 2B [ Danio rerio (zebrafish) ]

    Gene ID: 561643, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pwwp2bprovided by ZNC
    Official Full Name
    PWWP domain containing 2Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-110930-2
    See related
    Ensembl:ENSDARG00000101080 AllianceGenome:ZFIN:ZDB-GENE-110930-2
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Orthologous to human PWWP2B (PWWP domain containing 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pwwp2b in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (51710608..51729243)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (51485145..51503833)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase A Neighboring gene serine/threonine-protein kinase 32C Neighboring gene inositol polyphosphate-5-phosphatase A Neighboring gene zmp:0000000755 Neighboring gene LBH regulator of WNT signaling pathway Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene serum response factor b

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    PWWP domain-containing protein 2B
    Names
    PWWP domain containing 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      51710608..51729243
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001920829.9 → XP_001920864.3  PWWP domain-containing protein 2B

      UniProtKB/TrEMBL
      A0A0R4IGL9, A0A8M1QUX5
      Related
      ENSDARP00000133698.1, ENSDART00000163741.3
      Conserved Domains (1) summary
      cd05835
      Location:493 → 580
      Dnmt3b_related; The PWWP domain is an essential component of DNA methyltransferase 3 B (Dnmt3b) which is responsible for establishing DNA methylation patterns during embryogenesis and gametogenesis. In tumorigenesis, DNA methylation by Dnmt3b is known to play a role in ...
    Nucleotide Protein Strain
    Heading Accession and Version

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