arpin actin related protein 2/3 complex inhibitor [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arpinprovided by ZNC
Official Full Name: actin related protein 2/3 complex inhibitorprovided by ZNC
Primary source: ZFIN:ZDB-GENE-050417-304
See related: Ensembl:ENSDARG00000041085 AllianceGenome:ZFIN:ZDB-GENE-050417-304
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:112432; si:ch211-200o3.3
Summary: Involved in directional locomotion and negative regulation of cell migration. Predicted to be located in lamellipodium. Is expressed in intestinal bulb. Orthologous to human ARPIN (actin related protein 2/3 complex inhibitor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (21071007..21084906)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (21081941..21086911)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in directional locomotion	IDA Inferred from Direct Assay more info	PubMed
involved_in negative regulation of actin nucleation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of actin nucleation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of cell migration	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in negative regulation of cell migration	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in lamellipodium	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: arpin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.