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    ephx5 epoxide hydrolase 5 [ Danio rerio (zebrafish) ]

    Gene ID: 322331, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ephx5provided by ZNC
    Official Full Name
    epoxide hydrolase 5provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-1050
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-1050
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ephx1; ephx1l; wu:fb58c02; wu:fb62g01
    Summary
    Predicted to enable cis-stilbene-oxide hydrolase activity. Predicted to act upstream of or within lipid metabolic process and response to toxic substance. Predicted to be located in endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: suggests misassembly
    Orthologs
    all
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    Genomic context

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    See ephx5 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (33688350..33696076)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (33339770..33343339)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487422 Neighboring gene MAD2L1 binding protein Neighboring gene mono-ADP ribosylhydrolase 2 Neighboring gene uncharacterized LOC137487423 Neighboring gene cystatin C (amyloid angiopathy and cerebral hemorrhage) Neighboring gene fibronectin leucine rich transmembrane 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cis-stilbene-oxide hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ether hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to toxic substance IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    epoxide hydrolase 1
    Names
    epoxide hydrolase 1, like
    XP_005173080.4
    XP_021336553.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      33688350..33696076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021480878.2 → XP_021336553.1  epoxide hydrolase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9QAE5
      Conserved Domains (2) summary
      pfam00561
      Location:166 → 396
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam06441
      Location:72 → 180
      EHN; Epoxide hydrolase N terminus

    2. XM_005173023.5 → XP_005173080.4  epoxide hydrolase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M2BK97
      Conserved Domains (2) summary
      pfam00561
      Location:166 → 396
      Abhydrolase_1; alpha/beta hydrolase fold
      pfam06441
      Location:72 → 180
      EHN; Epoxide hydrolase N terminus
    Nucleotide Protein Strain
    Heading Accession and Version

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