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    pvalb3 parvalbumin 3 [ Danio rerio (zebrafish) ]

    Gene ID: 100000771, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pvalb3provided by ZNC
    Official Full Name
    parvalbumin 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-945
    See related
    Ensembl:ENSDARG00000022817 AllianceGenome:ZFIN:ZDB-GENE-040426-945
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56217; zgc:77798
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be active in cytoplasm. Is expressed in hypaxial myotome region and myotome. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See pvalb3 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (17705220..17707517, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (17583342..17585643, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene CCZ1 homolog, vacuolar protein trafficking and biogenesis associated Neighboring gene parvalbumin 9 Neighboring gene microRNA mir-2192 Neighboring gene parvalbumin 2 Neighboring gene uncharacterized LOC137496810 Neighboring gene microRNA 338-2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Parvalbumin isoforms in zebrafish. Friedberg F. Mol Biol Rep, 2005 Sep. PMID 16172917
    2. Serial analysis of gene expression in the skeletal muscles of zebrafish fed with a methylmercury-contaminated diet. Cambier S, et al. Environ Sci Technol, 2010 Jan 1. PMID 20039754
    3. Global Transcriptomic Analysis of Zebrafish Glucagon Receptor Mutant Reveals Its Regulated Metabolic Network. Kang Q, et al. Int J Mol Sci, 2020 Jan 22. PMID 31979106, Free PMC Article
    4. Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress. Ge G, et al. Int J Mol Sci, 2022 Jul 6. PMID 35886843, Free PMC Article
    5. Insights into electrosensory organ development, physiology and evolution from a lateral line-enriched transcriptome. Modrell MS, et al. Elife, 2017 Mar 27. PMID 28346141, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC56217, MGC77798

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    parvalbumin 3
    Names
    parvalbumin, beta

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200212.1 → NP_956506.1  parvalbumin 3 isoform 1b

      See identical proteins and their annotated locations for NP_956506.1

      Status: PROVISIONAL

      Source sequence(s)
      BC046001
      UniProtKB/TrEMBL
      F6PCJ6, Q6P5K2, Q7ZT36
      Related
      ENSDARP00000031690.5, ENSDART00000034914.7
      Conserved Domains (2) summary
      cd00051
      Location:43 → 108
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:44 → 107
      EF-hand_7; EF-hand domain pair

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      17705220..17707517 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005169450.5 → XP_005169507.1  parvalbumin 3 isoform X1

      See identical proteins and their annotated locations for XP_005169507.1

      UniProtKB/TrEMBL
      F6PCJ6, Q6P5K2, Q7ZT36
      Related
      ENSDARP00000121670.1, ENSDART00000142427.2
      Conserved Domains (2) summary
      cd00051
      Location:43 → 108
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:44 → 107
      EF-hand_7; EF-hand domain pair

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394834.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      149734..152030 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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