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    utp23 UTP23 small subunit processome component [ Danio rerio (zebrafish) ]

    Gene ID: 550514, updated on 9-Dec-2024

    Summary

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    Official Symbol
    utp23provided by ZNC
    Official Full Name
    UTP23 small subunit processome componentprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-353
    See related
    Ensembl:ENSDARG00000105012 AllianceGenome:ZFIN:ZDB-GENE-050417-353
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc04b12; wu:fc04b12; zgc:110214
    Summary
    Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to act upstream of or within rRNA processing. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; lens placode; optic vesicle; presumptive neural retina; and segmental plate. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human UTP23 (UTP23 small subunit processome component). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See utp23 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (45962056..45967718)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (46371401..46377098)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene trichorhinophalangeal syndrome I Neighboring gene uncharacterized LOC137488553 Neighboring gene eukaryotic translation initiation factor 3, subunit H, b Neighboring gene si:ch211-153f2.3 Neighboring gene uncharacterized protein C20orf202-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Cis-regulatory control of mammalian Trps1 gene expression. Abrar M, et al. J Exp Zool B Mol Dev Evol, 2024 Mar. PMID 38369890,
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables small ribosomal subunit rRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    rRNA-processing protein UTP23 homolog
    Names
    UTP23, small subunit (SSU) processome component, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017816.1 → NP_001017816.1  rRNA-processing protein UTP23 homolog

      See identical proteins and their annotated locations for NP_001017816.1

      Status: PROVISIONAL

      Source sequence(s)
      BC092802
      UniProtKB/TrEMBL
      Q568M1
      Conserved Domains (1) summary
      cd09866
      Location:2 → 148
      PIN_Fcf1-Utp23-H; PIN domain of rRNA-processing protein Fcf1- and Utp23-like homologs found in eukaryotes except fungi

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      45962056..45967718
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068215127.1 → XP_068071228.1  rRNA-processing protein UTP23 homolog isoform X1

      UniProtKB/TrEMBL
      A0A0R4IA74, A0A8M3B3U5
      Related
      ENSDARP00000130967.1, ENSDART00000169710.2
    Nucleotide Protein Strain
    Heading Accession and Version

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