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    lhfpl2a LHFPL tetraspan subfamily member 2a [ Danio rerio (zebrafish) ]

    Gene ID: 402962, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lhfpl2aprovided by ZNC
    Official Full Name
    LHFPL tetraspan subfamily member 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1839
    See related
    Ensembl:ENSDARG00000009653 AllianceGenome:ZFIN:ZDB-GENE-040426-1839
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    lhfpl2; zgc:77456
    Summary
    Predicted to be involved in development of primary female sexual characteristics; development of primary male sexual characteristics; and positive regulation of fertilization. Predicted to act upstream of or within single fertilization. Predicted to be active in membrane. Orthologous to human LHFPL2 (LHFPL tetraspan subfamily member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See lhfpl2a in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (301002..327032, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) Unplaced Scaffold NW_008805479.1 (927..1393)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene plasminogen receptor, C-terminal lysine transmembrane protein Neighboring gene ral guanine nucleotide dissociation stimulator Neighboring gene arylsulfatase B Neighboring gene zinc finger protein 462

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77456

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in development of primary female sexual characteristics ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in development of primary male sexual characteristics ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in positive regulation of fertilization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within single fertilization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LHFPL tetraspan subfamily member 2a protein
    Names
    lipoma HMGIC fusion partner-like 2 protein pseudogene
    lipoma HMGIC fusion partner-like 2a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205663.1 → NP_991226.1  LHFPL tetraspan subfamily member 2a protein

      See identical proteins and their annotated locations for NP_991226.1

      Status: PROVISIONAL

      Source sequence(s)
      BC065671
      UniProtKB/Swiss-Prot
      Q6P0C6
      UniProtKB/TrEMBL
      A0A8M9P387
      Related
      ENSDARP00000126208.2, ENSDART00000151613.2
      Conserved Domains (1) summary
      pfam10242
      Location:9 → 201
      L_HMGIC_fpl; Lipoma HMGIC fusion partner-like protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      301002..327032 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468792.2 → XP_021324467.1  LHFPL tetraspan subfamily member 2a protein isoform X1

      UniProtKB/Swiss-Prot
      Q6P0C6
      UniProtKB/TrEMBL
      A0A8M9P387
      Conserved Domains (1) summary
      pfam10242
      Location:9 → 201
      L_HMGIC_fpl; Lipoma HMGIC fusion partner-like protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6P0C6.1 GenPept UniProtKB/Swiss-Prot:Q6P0C6

    Gene LinkOut

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