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    leprot leptin receptor overlapping transcript [ Danio rerio (zebrafish) ]

    Gene ID: 550484, updated on 9-Dec-2024

    Summary

    Official Symbol
    leprotprovided by ZNC
    Official Full Name
    leptin receptor overlapping transcriptprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-314
    See related
    AllianceGenome:ZFIN:ZDB-GENE-050417-314
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    OB-RGRP; zgc:112430
    Summary
    Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and negative regulation of growth hormone receptor signaling pathway. Predicted to be located in Golgi membrane and endosome membrane. Predicted to be active in endosome. Is expressed in pharynx and pronephric duct. Orthologous to human LEPROT (leptin receptor overlapping transcript). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
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    Genomic context

    See leprot in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (14655132..14661146, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (14986542..14992556, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 4B, cAMP-specific b Neighboring gene proline-rich protein 36 Neighboring gene uncharacterized LOC101882800 Neighboring gene U2 spliceosomal RNA Neighboring gene U2 spliceosomal RNA Neighboring gene U2 spliceosomal RNA

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    leptin receptor gene-related protein
    Names
    OB-R gene-related protein
    endospanin-1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017787.1NP_001017787.1  leptin receptor gene-related protein

      See identical proteins and their annotated locations for NP_001017787.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093304
      UniProtKB/Swiss-Prot
      Q561T9
      Conserved Domains (1) summary
      pfam04133
      Location:7123
      Vps55; Vacuolar protein sorting 55

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      14655132..14661146 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)