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    pcdh10b protocadherin 10b [ Danio rerio (zebrafish) ]

    Gene ID: 360138, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pcdh10bprovided by ZNC
    Official Full Name
    protocadherin 10bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030721-4
    See related
    Ensembl:ENSDARG00000102824 AllianceGenome:ZFIN:ZDB-GENE-030721-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    pcdh10; wu:fq16b02
    Summary
    Predicted to enable calcium ion binding activity. Acts upstream of or within paraxial mesoderm development; somitogenesis; and thalamus development. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior axial hypoblast; mesoderm; nervous system; spinal cord neural tube; and trunk. Orthologous to human PCDH10 (protocadherin 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See pcdh10b in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (42978695..43000864, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (42611441..42633630, complement)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137487539 Neighboring gene uncharacterized LOC137487616 Neighboring gene uncharacterized LOC103910029 Neighboring gene uncharacterized LOC137487617

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within paraxial mesoderm development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within somitogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thalamus development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protocadherin-10b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_182885.1 → NP_878305.1  protocadherin-10b precursor

      See identical proteins and their annotated locations for NP_878305.1

      Status: PROVISIONAL

      Source sequence(s)
      AB086625
      UniProtKB/TrEMBL
      A0A8N7UZV6, Q805F0
      Related
      ENSDARP00000134223.1, ENSDART00000162714.3
      Conserved Domains (3) summary
      cd11304
      Location:233 → 333
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam08266
      Location:17 → 99
      Cadherin_2; Cadherin-like
      pfam16492
      Location:677 → 809
      Cadherin_C_2; Cadherin cytoplasmic C-terminal

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      42978695..43000864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009291096.4 → XP_009289371.1  protocadherin-10b isoform X1

      UniProtKB/TrEMBL
      A0A8M3B0C3
      Conserved Domains (3) summary
      cd11304
      Location:233 → 333
      Cadherin_repeat; Cadherin tandem repeat domain
      pfam08266
      Location:17 → 99
      Cadherin_2; Cadherin-like
      pfam16492
      Location:677 → 809
      Cadherin_C_2; Cadherin cytoplasmic C-terminal
    Nucleotide Protein Strain
    Heading Accession and Version

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