U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ly75 lymphocyte antigen 75 [ Danio rerio (zebrafish) ]

    Gene ID: 504036, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ly75provided by ZNC
    Official Full Name
    lymphocyte antigen 75provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050309-166
    See related
    Ensembl:ENSDARG00000053113 AllianceGenome:ZFIN:ZDB-GENE-050309-166
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7150926; si:dkey-78p20.2
    Summary
    Predicted to enable signaling receptor activity. Predicted to act upstream of or within endocytosis. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in heart and macrophage. Orthologous to several human genes including LY75 (lymphocyte antigen 75). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ly75 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (11120634..11193055)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (11136989..11209434)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene integrin, beta 6 Neighboring gene phospholipase A2 receptor 1 Neighboring gene myomesin 2a Neighboring gene lengsin, lens protein with glutamine synthetase domain

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Alterations in cardiac DNA methylation in human dilated cardiomyopathy. Haas J, et al. EMBO Mol Med, 2013 Mar. PMID 23341106, Free PMC Article
    2. Identification and migration of primordial germ cells in Atlantic salmon, Salmo salar: characterization of vasa, dead end, and lymphocyte antigen 75 genes. Nagasawa K, et al. Mol Reprod Dev, 2013 Feb. PMID 23239145, Free PMC Article
    3. Molecular insights of organochlorine biocide-induced toxicity in zebrafish: Whole-adult-organism toxicogenomics, targeted gene expression and histological analyses. Lui EY, et al. J Genet Genomics, 2016 Aug 20. PMID 27503704
    4. Induced autoimmunity against gonadal proteins affects gonadal development in juvenile zebrafish. Presslauer C, et al. PLoS One, 2014. PMID 25436775, Free PMC Article
    5. Molecular dissection of the migrating posterior lateral line primordium during early development in zebrafish. Gallardo VE, et al. BMC Dev Biol, 2010 Dec 13. PMID 21144052, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endocytosis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    lymphocyte antigen 75

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      11120634..11193055
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009305864.4 → XP_009304139.1  lymphocyte antigen 75

      UniProtKB/TrEMBL
      A0A8M3BDJ8, F1QS24
      Related
      ENSDARP00000011500.7, ENSDART00000026135.10
      Conserved Domains (4) summary
      smart00059
      Location:160 → 208
      FN2; Fibronectin type 2 domain
      cd00037
      Location:227 → 340
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
      smart00034
      Location:958 → 1093
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
      smart00458
      Location:37 → 132
      RICIN; Ricin-type beta-trefoil
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools