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    siva1 SIVA1, apoptosis-inducing factor [ Danio rerio (zebrafish) ]

    Gene ID: 571845, updated on 9-Dec-2024

    Summary

    Official Symbol
    siva1provided by ZNC
    Official Full Name
    SIVA1, apoptosis-inducing factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050506-57
    See related
    Ensembl:ENSDARG00000114552 AllianceGenome:ZFIN:ZDB-GENE-050506-57
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:6902407
    Summary
    Predicted to enable CD27 receptor binding activity. Predicted to be involved in extrinsic apoptotic signaling pathway. Is expressed in male organism. Orthologous to human SIVA1 (SIVA1 apoptosis inducing factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See siva1 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (1360044..1369344)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (699778..709078)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene inverted formin 2 Neighboring gene adenylosuccinate synthase 1 Neighboring gene zinc finger and BTB domain containing 42 Neighboring gene v-akt murine thymoma viral oncogene homolog 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables CD27 receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in extrinsic apoptotic signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    apoptosis regulatory protein Siva

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001327928.1NP_001314857.1  apoptosis regulatory protein Siva

      Status: VALIDATED

      Source sequence(s)
      CR855301, EH453280, EH453513, EH456122, EH510676
      UniProtKB/TrEMBL
      A0A2R8QL23, A0A8M1P8I3
      Related
      ENSDARP00000156081.1, ENSDART00000184561.1
      Conserved Domains (1) summary
      pfam05458
      Location:1171
      Siva; Cd27 binding protein (Siva)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      1360044..1369344
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)