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    btbd6a BTB (POZ) domain containing 6a [ Danio rerio (zebrafish) ]

    Gene ID: 100141360, updated on 9-Dec-2024

    Summary

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    Official Symbol
    btbd6aprovided by ZNC
    Official Full Name
    BTB (POZ) domain containing 6aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080218-26
    See related
    Ensembl:ENSDARG00000076440 AllianceGenome:ZFIN:ZDB-GENE-080218-26
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    btbd6b; zgc:172197
    Summary
    Acts upstream of or within regulation of neurogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Is expressed in nervous system; neuroblasts; posterior neural keel; posterior neural plate; and spinal cord neural tube. Orthologous to human BTBD6 (BTB domain containing 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See btbd6a in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (33394113..33399828, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (33263661..33269370, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110440192 Neighboring gene zgc:172120 Neighboring gene BRF1 general transcription factor IIIB subunit a Neighboring gene finTRIM family, member 80 Neighboring gene finTRIM family, member 81

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. A feedback loop mediated by degradation of an inhibitor is required to initiate neuronal differentiation. Sobieszczuk DF, et al. Genes Dev, 2010 Jan 15. PMID 20080956, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neurogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of neurogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of neurogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BTB/POZ domain-containing protein 6-A
    Names
    BTB/POZ domain-containing protein 6-B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001114925.2 → NP_001108397.2  BTB/POZ domain-containing protein 6-A isoform 1

      Status: VALIDATED

      Source sequence(s)
      CU855940
      UniProtKB/Swiss-Prot
      A9JRD8
      Related
      ENSDARP00000146109.1, ENSDART00000182601.1

    2. NM_001431077.1 → NP_001418006.1  BTB/POZ domain-containing protein 6-A isoform 2

      Status: VALIDATED

      Source sequence(s)
      CU855940
      UniProtKB/Swiss-Prot
      A9JRD8
      UniProtKB/TrEMBL
      A0A8M2BHZ5

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      33394113..33399828 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A9JRD8.2 GenPept UniProtKB/Swiss-Prot:A9JRD8

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