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    p2rx4a purinergic receptor P2X, ligand-gated ion channel, 4a [ Danio rerio (zebrafish) ]

    Gene ID: 259258, updated on 9-Dec-2024

    Summary

    Official Symbol
    p2rx4aprovided by ZNC
    Official Full Name
    purinergic receptor P2X, ligand-gated ion channel, 4aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-020806-2
    See related
    Ensembl:ENSDARG00000044752 AllianceGenome:ZFIN:ZDB-GENE-020806-2
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    p2x4; p2rx4; wu:fi03f02
    Summary
    Enables ATP binding activity; CTP binding activity; and extracellularly ATP-gated monoatomic cation channel activity. Acts upstream of or within calcium ion transport. Located in membrane. Part of monoatomic ion channel complex. Orthologous to human P2RX4 (purinergic receptor P2X 4). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See p2rx4a in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (15723206..15732398)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (15626683..15636424)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase theta 1b Neighboring gene D-dopachrome tautomerase Neighboring gene isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta Neighboring gene protein tyrosine phosphatase receptor type A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in lysosomal membrane  
    located_in lysosome  
    located_in membrane PubMed 
    located_in membrane  
    part_of monoatomic ion channel complex PubMed 
    is_active_in plasma membrane  
    located_in plasma membrane  
    part_of transmembrane transporter complex PubMed 

    General protein information

    Preferred Names
    P2X purinoceptor 4a
    Names
    etID14865.21
    zP2X4.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153653.1 → NP_705939.1  P2X purinoceptor 4a

      See identical proteins and their annotated locations for NP_705939.1

      Status: PROVISIONAL

      Source sequence(s)
      AF317643
      UniProtKB/Swiss-Prot
      F8W463, Q6NYR1, Q98TZ0
      Related
      ENSDARP00000123980.1, ENSDART00000149126.3
      Conserved Domains (1) summary
      pfam00864
      Location:16 → 380
      P2X_receptor; ATP P2X receptor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      15723206..15732398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395082.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      27016..36208
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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