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    Saxo5 stabilizer of axonemal microtubules 5 [ Mus musculus (house mouse) ]

    Gene ID: 76406, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Saxo5provided by MGI
    Official Full Name
    stabilizer of axonemal microtubules 5provided by MGI
    Primary source
    MGI:MGI:1923656
    See related
    Ensembl:ENSMUSG00000040340 AllianceGenome:MGI:1923656
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tex45; 1700019B03Rik
    Summary
    Is expressed in ductus deferens; prostate gland; and testis. Orthologous to human SAXO5 (stabilizer of axonemal microtubules 5). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 25.3) See more
    Orthologs
    human all
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    Genomic context

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    See Saxo5 in Genome Data Viewer
    Location:
    8 A1.1; 8 1.92 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (3515966..3537183)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (3466713..3487183)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:3354554-3354663 Neighboring gene predicted gene, 30369 Neighboring gene Rho/Rac guanine nucleotide exchange factor 18 Neighboring gene STARR-seq mESC enhancer starr_20578 Neighboring gene predicted gene, 46029 Neighboring gene STARR-positive B cell enhancer ABC_E10487 Neighboring gene peroxisomal biogenesis factor 11 gamma Neighboring gene zinc finger protein 358 Neighboring gene mucolipin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice. Miyata H, et al. Proc Natl Acad Sci U S A, 2016 Jul 12. PMID 27357688, Free PMC Article
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    stabilizer of axonemal microtubules 5
    Names
    testis expressed 45

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029598.1 → NP_083874.1  stabilizer of axonemal microtubules 5

      See identical proteins and their annotated locations for NP_083874.1

      Status: PROVISIONAL

      Source sequence(s)
      AK006106, BC050809
      Consensus CDS
      CCDS52467.1
      UniProtKB/TrEMBL
      G3XA23
      Related
      ENSMUSP00000043586.7, ENSMUST00000047265.13
      Conserved Domains (1) summary
      pfam15373
      Location:58 → 499
      DUF4601; Domain of unknown function (DUF4601)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      3515966..3537183
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313004.3 → XP_017168493.1  stabilizer of axonemal microtubules 5 isoform X2

      UniProtKB/TrEMBL
      G3XA23
      Conserved Domains (1) summary
      pfam15373
      Location:58 → 499
      DUF4601; Domain of unknown function (DUF4601)

    2. XM_006508921.1 → XP_006508984.1  stabilizer of axonemal microtubules 5 isoform X1

      Conserved Domains (1) summary
      pfam15373
      Location:72 → 513
      DUF4601; Domain of unknown function (DUF4601)

    3. XM_006508922.1 → XP_006508985.1  stabilizer of axonemal microtubules 5 isoform X3

      Conserved Domains (1) summary
      pfam15373
      Location:72 → 444
      DUF4601; Domain of unknown function (DUF4601)

    4. XM_006508924.2 → XP_006508987.1  stabilizer of axonemal microtubules 5 isoform X5

      Conserved Domains (1) summary
      pfam15373
      Location:72 → 269
      DUF4601; Domain of unknown function (DUF4601)

    5. XM_006508923.1 → XP_006508986.1  stabilizer of axonemal microtubules 5 isoform X4

      UniProtKB/TrEMBL
      Q80YS7
      Related
      ENSMUSP00000123746.2, ENSMUST00000159076.8
      Conserved Domains (1) summary
      pfam15373
      Location:72 → 341
      DUF4601; Domain of unknown function (DUF4601)

    6. XM_006508925.2 → XP_006508988.1  stabilizer of axonemal microtubules 5 isoform X6

      Conserved Domains (1) summary
      pfam15373
      Location:72 → 270
      DUF4601; Domain of unknown function (DUF4601)

    7. XM_017313002.3 → XP_017168491.1  stabilizer of axonemal microtubules 5 isoform X2

      UniProtKB/TrEMBL
      G3XA23
      Conserved Domains (1) summary
      pfam15373
      Location:58 → 499
      DUF4601; Domain of unknown function (DUF4601)

    8. XM_017313005.2 → XP_017168494.1  stabilizer of axonemal microtubules 5 isoform X2

      UniProtKB/TrEMBL
      G3XA23
      Related
      ENSMUSP00000124916.2, ENSMUST00000161680.2
      Conserved Domains (1) summary
      pfam15373
      Location:58 → 499
      DUF4601; Domain of unknown function (DUF4601)

    9. XM_017313003.2 → XP_017168492.1  stabilizer of axonemal microtubules 5 isoform X2

      UniProtKB/TrEMBL
      G3XA23
      Conserved Domains (1) summary
      pfam15373
      Location:58 → 499
      DUF4601; Domain of unknown function (DUF4601)
    Nucleotide Protein Strain
    Heading Accession and Version

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