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    Syf2 SYF2 homolog, RNA splicing factor (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 68592, updated on 9-Dec-2024

    Summary

    Official Symbol
    Syf2provided by MGI
    Official Full Name
    SYF2 homolog, RNA splicing factor (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1915842
    See related
    Ensembl:ENSMUSG00000028821 AllianceGenome:MGI:1915842
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    p29; mp29; Cbpin; Ntc31; Gcipip; D4Bwg1551e; 1110018L13Rik
    Summary
    Acts upstream of or within several processes, including gastrulation; in utero embryonic development; and mitotic G2 DNA damage checkpoint signaling. Located in nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; and embryo. Orthologous to human SYF2 (SYF2 pre-mRNA splicing factor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in bladder adult (RPKM 34.8), liver E14 (RPKM 30.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Syf2 in Genome Data Viewer
    Location:
    4 D3; 4 67.15 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (134658291..134664848)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134930980..134937537)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 50A Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:134474397-134474585 Neighboring gene STARR-positive B cell enhancer ABC_E6231 Neighboring gene STARR-positive B cell enhancer ABC_E8812 Neighboring gene STARR-seq mESC enhancer starr_11694 Neighboring gene arginine/serine rich protein 1 Neighboring gene STARR-seq mESC enhancer starr_11697 Neighboring gene DRG (dorsal root ganglion) regulatory region upstream of Runx3 Neighboring gene predicted gene, 42327 Neighboring gene predicted gene 16225

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of Prp19 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of U2-type catalytic step 2 spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of catalytic step 2 spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of post-mRNA release spliceosomal complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-splicing factor SYF2
    Names
    CCNDBP1 interactor
    GCIP-interacting protein p29 (Gcipip)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026780.3NP_081056.1  pre-mRNA-splicing factor SYF2

      See identical proteins and their annotated locations for NP_081056.1

      Status: PROVISIONAL

      Source sequence(s)
      AL611963
      Consensus CDS
      CCDS18781.1
      UniProtKB/Swiss-Prot
      Q9D198
      Related
      ENSMUSP00000030622.3, ENSMUST00000030622.3
      Conserved Domains (1) summary
      pfam08231
      Location:89237
      SYF2; SYF2 splicing factor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      134658291..134664848
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)