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    pnn-1 Pinin/SDK/MemA protein domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179783, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pnn-1
    Official Full Name
    Pinin/SDK/MemA protein domain-containing protein
    Primary source
    WormBase:WBGene00011308
    Locus tag
    CELE_R186.7
    See related
    AllianceGenome:WB:WBGene00011308
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in nucleus. Predicted to be part of catalytic step 2 spliceosome. Orthologous to human PNN (pinin, desmosome associated protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pnn-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (12971110..12973281)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene 39S ribosomal protein L33, mitochondrial Neighboring gene MoeA N-terminal and linker domain-containing protein Neighboring gene BTB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. C. elegans ORFeome version 1.1: experimental verification of the genome annotation and resource for proteome-scale protein expression. Reboul J, et al. Nat Genet, 2003 May. PMID 12679813
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Pinin/SDK/MemA protein domain-containing protein
    NP_506247.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12971110..12973281
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073846.6 → NP_506247.1  Pinin/SDK/MemA protein domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506247.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95ZQ5
      Conserved Domains (2) summary
      pfam04696
      Location:154 → 273
      Pinin_SDK_memA; pinin/SDK/memA/ protein conserved region
      pfam04697
      Location:6 → 146
      Pinin_SDK_N; pinin/SDK conserved region
    Nucleotide Protein
    Heading Accession and Version

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