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    ptr-25 SSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176469, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ptr-25
    Official Full Name
    SSD domain-containing protein
    Primary source
    WormBase:WBGene00009653
    Locus tag
    CELE_F43D9.1
    See related
    AllianceGenome:WB:WBGene00009653
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endocytosis and molting cycle. Located in centrosome. Is expressed in head neurons; interneuron; and muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ptr-25 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    19
    Sequence:
    Chromosome: III; NC_003281.10 (10488124..10500239)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene BTB domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ras-related protein Rab-33 Neighboring gene TAFII28-like protein domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of a novel gene expressed in neuromuscular tissues and centrosomes in Caenorhabditis elegans. Kwon S, et al. Cell Biochem Funct, 2001 Jun. PMID 11335932
    2. Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking. Maza N, et al. Nat Neurosci, 2022 Sep. PMID 35982154, Free PMC Article
    3. The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization. Ahn S, et al. Cell Rep, 2022 Apr 12. PMID 35417689
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SSD domain-containing protein
    NP_499313.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10488124..10500239
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066912.7 → NP_499313.2  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499313.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECF2
      Conserved Domains (1) summary
      cl25655
      Location:328 → 1021
      Patched; Patched family
    Nucleotide Protein
    Heading Accession and Version

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