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    rnh-1.3 RNase H type-1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 182229, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rnh-1.3
    Official Full Name
    RNase H type-1 domain-containing protein
    Primary source
    WormBase:WBGene00007303
    Locus tag
    CELE_C04F12.9
    See related
    AllianceGenome:WB:WBGene00007303
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA-DNA hybrid ribonuclease activity. Predicted to be involved in DNA replication, removal of RNA primer. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rnh-1.3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (9710088..9710745, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Transposase Neighboring gene ncRNA Neighboring gene CAAX prenyl protease 1 homolog Neighboring gene BSD domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genomic analysis of the telomeric length effect on organismic lifespan in Caenorhabditis elegans. Park MC, et al. Biochem Biophys Res Commun, 2010 May 28. PMID 20430011
    2. Stage-specific expression of Caenorhabditis elegans ribonuclease H1 enzymes with different substrate specificities and bivalent cation requirements. Kochiwa H, et al. FEBS J, 2006 Jan. PMID 16403028
    3. DEPS-1 promotes P-granule assembly and RNA interference in C. elegans germ cells. Spike CA, et al. Development, 2008 Mar. PMID 18234720, Free PMC Article
    4. Interacting endogenous and exogenous RNAi pathways in Caenorhabditis elegans. Lee RC, et al. RNA, 2006 Apr. PMID 16489184, Free PMC Article
    5. A gene-centered C. elegans protein-DNA interaction network. Deplancke B, et al. Cell, 2006 Jun 16. PMID 16777607

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA-DNA hybrid ribonuclease activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA-DNA hybrid ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA replication, removal of RNA primer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    RNase H type-1 domain-containing protein
    NP_492581.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9710088..9710745 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060180.4 → NP_492581.1  RNase H type-1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492581.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XVE6
      Conserved Domains (1) summary
      cd09280
      Location:6 → 135
      RNase_HI_eukaryote_like; Eukaryotic RNase H is essential and is longer and more complex than their prokaryotic counterparts
    Nucleotide Protein
    Heading Accession and Version

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