U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cwp-5 Coexpressed With Polycystins [ Caenorhabditis elegans ]

    Gene ID: 185977, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cwp-5
    Official Full Name
    Coexpressed With Polycystins
    Primary source
    WormBase:WBGene00009844
    Locus tag
    CELE_F48C11.2
    See related
    AllianceGenome:WB:WBGene00009844
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in neuronal signal transduction and response to hermaphrodite contact. Located in cell body; dendrite; and non-motile cilium. Is expressed in CEM; HOB; and ray neuron type B. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cwp-5 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (13182114..13189961, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Mps One Binder (Mats/MOB1) homolog;Mps one binder kinase activator-like 2 Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA Neighboring gene Guanine nucleotide-binding protein alpha-6 subunit Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A latent capacity of the C. elegans polycystins to disrupt sensory transduction is repressed by the single-pass ciliary membrane protein CWP-5. Miller RM, et al. Dis Model Mech, 2010 Jul-Aug. PMID 20223935, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The novel single-pass membrane protein CWP-5 is necessary for polycystin signaling during the response step of mating behavior.
      Title: A latent capacity of the C. elegans polycystins to disrupt sensory transduction is repressed by the single-pass ciliary membrane protein CWP-5.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in neuronal signal transduction IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in response to hermaphrodite contact IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in non-motile cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Coexpressed With Polycystins
    NP_001359731.1
    • Product from WormBase gene class cwp;
      Partially confirmed by transcript evidence
    NP_001359732.1
    • Product from WormBase gene class cwp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      13182114..13189961 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373548.2 → NP_001359731.1  Coexpressed With Polycystins [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6VQ87
      Conserved Domains (2) summary
      PHA03247
      Location:436 → 639
      PHA03247; large tegument protein UL36; Provisional
      cl02432
      Location:20 → 149
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    2. NM_001373549.3 → NP_001359732.1  Coexpressed With Polycystins [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B6VQ88
      Conserved Domains (1) summary
      PHA03247
      Location:319 → 522
      PHA03247; large tegument protein UL36; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools