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    rhr-1 Ammonium transporter AmtB-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178927, updated on 9-Dec-2024

    Summary

    Official Symbol
    rhr-1
    Official Full Name
    Ammonium transporter AmtB-like domain-containing protein
    Primary source
    WormBase:WBGene00004358
    Locus tag
    CELE_F08F3.3
    See related
    AllianceGenome:WB:WBGene00004358
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables ammonium channel activity. Involved in ammonium transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including amphid socket cell; excretory cell; hypodermis; rectal gland cell; and reproductive system. Human ortholog(s) of this gene implicated in Rh deficiency syndrome; Rh isoimmunization; hemolytic anemia; and overhydrated hereditary stomatocytosis. Orthologous to several human genes including RHAG (Rh associated glycoprotein); RHBG (Rh family B glycoprotein); and RHCG (Rh family C glycoprotein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rhr-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (5428160..5430431)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene CYtochrome P450 family Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene WSN domain-containing protein Neighboring gene Phospholipid/glycerol acyltransferase domain-containing protein;putative glycerol-3-phosphate acyltransferase, mitochondrial Neighboring gene SNAPc (Small Nuclear RNA Activating Complex) homolog

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ammonium channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ammonium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ammonium channel activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in ammonium homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ammonium transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ammonium transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ammonium transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Ammonium transporter AmtB-like domain-containing protein
    NP_001370490.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5428160..5430431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001383307.2NP_001370490.1  Ammonium transporter AmtB-like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22947, Q9N2M4
      Conserved Domains (1) summary
      pfam00909
      Location:20430
      Ammonium_transp; Ammonium Transporter Family