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    cdh-9 Cadherin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186608, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cdh-9
    Official Full Name
    Cadherin domain-containing protein
    Primary source
    WormBase:WBGene00000401
    Locus tag
    CELE_F59C12.1
    See related
    AllianceGenome:WB:WBGene00000401
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules. Predicted to be located in membrane. Orthologous to several human genes including PCDH1 (protocadherin 1); PCDH20 (protocadherin 20); and PCDH7 (protocadherin 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cdh-9 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    14
    Sequence:
    Chromosome: X; NC_003284.9 (16595231..16602245)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene tRNA-Val Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Angiomotin_C domain-containing protein Neighboring gene tRNA-Asp Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The cadherin superfamily. Pettitt J. WormBook, 2005 Dec 29. PMID 18050421, Free PMC Article
    2. Cell adhesion receptors in C. elegans. Cox EA, et al. J Cell Sci, 2004 Apr 15. PMID 15090591
    3. Cadherin superfamily proteins in Caenorhabditis elegans and Drosophila melanogaster. Hill E, et al. J Mol Biol, 2001 Feb 2. PMID 11162110
    4. Intestinal tube formation in Caenorhabditis elegans requires vang-1 and egl-15 signaling. Hoffmann M, et al. Dev Biol, 2010 Mar 15. PMID 20004187
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cadherin domain-containing protein
    NP_001379384.1
    • Confirmed by transcript evidence
    NP_510685.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      16595231..16602245
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392909.1 → NP_001379384.1  Cadherin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7R9SUP0
      Conserved Domains (2) summary
      cd11304
      Location:135 → 234
      Cadherin_repeat; Cadherin tandem repeat domain
      cl29226
      Location:80 → 129
      Cadherin; Cadherin domain

    2. NM_078284.6 → NP_510685.2  Cadherin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510685.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21035
      Conserved Domains (2) summary
      cd11304
      Location:135 → 234
      Cadherin_repeat; Cadherin tandem repeat domain
      cl09101
      Location:80 → 129
      E_set; Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus
    Nucleotide Protein
    Heading Accession and Version

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