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    pitr-3 Phosphate transporter [ Caenorhabditis elegans ]

    Gene ID: 181858, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pitr-3
    Official Full Name
    Phosphate transporter
    Primary source
    WormBase:WBGene00015055
    Locus tag
    CELE_B0222.3
    See related
    AllianceGenome:WB:WBGene00015055
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Is expressed in hypodermis; pharynx; and reproductive system. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pitr-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (9138946..9141397, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Phosphate transporter Neighboring gene ncRNA Neighboring gene Sphingosine Phosphate Lyase Neighboring gene BPTI/Kunitz inhibitor domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A starvation-induced noncoding RNA modulates expression of Dicer-regulated genes. Hellwig S, et al. Proc Natl Acad Sci U S A, 2008 Sep 2. PMID 18723671, Free PMC Article
    2. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphate transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables symporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in phosphate ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phosphate ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Phosphate transporter
    NP_505371.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      9138946..9141397 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072970.6 → NP_505371.2  Phosphate transporter [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505371.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17455
      Conserved Domains (2) summary
      COG0306
      Location:31 → 490
      PitA; Phosphate/sulfate permease [Inorganic ion transport and metabolism]
      pfam01384
      Location:383 → 481
      PHO4; Phosphate transporter family
    Nucleotide Protein
    Heading Accession and Version

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