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    spe-12 Uncharacterized protein [ Caenorhabditis elegans ]

    Gene ID: 172606, updated on 9-Dec-2024

    Summary

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    Official Symbol
    spe-12
    Official Full Name
    Uncharacterized protein
    Primary source
    WormBase:WBGene00004966
    Locus tag
    CELE_T02E1.1
    See related
    AllianceGenome:WB:WBGene00004966
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in spermatid development. Located in plasma membrane. Is expressed in spermatid and in male. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See spe-12 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (8224539..8226297, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Protein dhs-3 Neighboring gene C3H1-type domain-containing protein Neighboring gene Fungal_trans domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FERM domain-containing protein Neighboring gene Ovule protein;Secreted protein Neighboring gene Nematode Specific Peptide family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. spe-12 encodes a sperm cell surface protein that promotes spermiogenesis in Caenorhabditis elegans. Nance J, et al. Genetics, 1999 May. PMID 10224255, Free PMC Article
    2. Initiation of spermiogenesis in C. elegans: a pharmacological and genetic analysis. Shakes DC, et al. Dev Biol, 1989 Jul. PMID 2731646
    3. Dynamic localization of SPE-9 in sperm: a protein required for sperm-oocyte interactions in Caenorhabditis elegans. Zannoni S, et al. BMC Dev Biol, 2003 Dec 3. PMID 14653860, Free PMC Article
    4. Sperm motility and MSP. Smith H. WormBook, 2006 Feb 1. PMID 18050481, Free PMC Article
    5. Regulation of sperm activation by SWM-1 is required for reproductive success of C. elegans males. Stanfield GM, et al. Curr Biol, 2006 Feb 7. PMID 16461278

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Uncharacterized protein
    NP_492242.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8224539..8226297 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059841.2 → NP_492242.1  Uncharacterized protein CELE_T02E1.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492242.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEF3
    Nucleotide Protein
    Heading Accession and Version

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