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    T10B11.6 Transmembrane protein 53 [ Caenorhabditis elegans ]

    Gene ID: 172424, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T10B11.6
    Official Full Name
    Transmembrane protein 53
    Primary source
    WormBase:WBGene00020402
    Locus tag
    CELE_T10B11.6
    See related
    AllianceGenome:WB:WBGene00020402
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Located in mitochondrion. Is expressed in several structures, including distal tip cell; head mesodermal cell; nervous system; non-striated muscle; and rectal epithelium. Human ortholog(s) of this gene implicated in craniotubular dysplasia Ikegawa type. Orthologous to human TMEM53 (transmembrane protein 53). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T10B11.6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    7
    Sequence:
    Chromosome: I; NC_003279.8 (6943176..6945358, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin-like domain-containing protein Neighboring gene DUF1273 family protein Neighboring gene Protein hrde-4 Neighboring gene Putative pterin-4-alpha-carbinolamine dehydratase Neighboring gene BACK domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans. Robert VJ, et al. Development, 2023 Nov 1. PMID 37818613, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    Transmembrane protein 53
    NP_491980.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6943176..6945358 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059579.6 → NP_491980.1  Transmembrane protein 53 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491980.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TZH8
      Conserved Domains (1) summary
      pfam05705
      Location:69 → 317
      DUF829; Eukaryotic protein of unknown function (DUF829)
    Nucleotide Protein
    Heading Accession and Version

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