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    Y71F9B.2 Phosphatidate cytidylyltransferase, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 171836, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y71F9B.2
    Official Full Name
    Phosphatidate cytidylyltransferase, mitochondrial
    Primary source
    WormBase:WBGene00022126
    Locus tag
    CELE_Y71F9B.2
    See related
    AllianceGenome:WB:WBGene00022126
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphatidate cytidylyltransferase activity. Predicted to be involved in CDP-diacylglycerol biosynthetic process and cardiolipin biosynthetic process. Predicted to be extrinsic component of mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 56. Orthologous to human TAMM41 (TAM41 mitochondrial translocator assembly and maintenance homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y71F9B.2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (2731562..2735371)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene putative small nuclear ribonucleoprotein G Neighboring gene Receptor expression-enhancing protein Neighboring gene eLRR (extracellular Leucine-Rich Repeat) ONly Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Germline Maintenance Through the Multifaceted Activities of GLH/Vasa in Caenorhabditis elegans P Granules. Marnik EA, et al. Genetics, 2019 Nov. PMID 31506335, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidate cytidylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidate cytidylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidate cytidylyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in CDP-diacylglycerol biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in CDP-diacylglycerol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cardiolipin biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cardiolipin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cardiolipin biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extrinsic component of mitochondrial inner membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Phosphatidate cytidylyltransferase, mitochondrial
    NP_001293366.1
    • Confirmed by transcript evidence
    NP_491034.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2731562..2735371
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058633.2 → NP_491034.1  Phosphatidate cytidylyltransferase, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491034.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9N4G7
      Conserved Domains (1) summary
      pfam09139
      Location:4 → 316
      Mmp37; Mitochondrial matrix Mmp37

    2. NM_001306437.3 → NP_001293366.1  Phosphatidate cytidylyltransferase, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293366.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BTI5
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N4G7.2

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