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    slr-2 Synthetic with Lin-35/Rb [ Caenorhabditis elegans ]

    Gene ID: 190396, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slr-2
    Official Full Name
    Synthetic with Lin-35/Rb
    Primary source
    WormBase:WBGene00013350
    Locus tag
    CELE_Y59A8B.13
    See related
    AllianceGenome:WB:WBGene00013350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See slr-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    10
    Sequence:
    Chromosome: V; NC_003283.11 (18087123..18098118)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene MATH domain-containing protein Neighboring gene Serine/threonine-protein kinase par-4 Neighboring gene Deoxyribonuclease TATDN2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Active transcriptomic and proteomic reprogramming in the C. elegans nucleotide excision repair mutant xpa-1. Arczewska KD, et al. Nucleic Acids Res, 2013 May 1. PMID 23580547, Free PMC Article
    2. Coordinated regulation of intestinal functions in C. elegans by LIN-35/Rb and SLR-2. Kirienko NV, et al. PLoS Genet, 2008 Apr 25. PMID 18437219, Free PMC Article
    3. Box C/D small nucleolar ribonucleoproteins regulate mitochondrial surveillance and innate immunity. Tjahjono E, et al. PLoS Genet, 2022 Mar. PMID 35275914, Free PMC Article
    4. SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network. Kirienko NV, et al. EMBO J, 2010 Feb 17. PMID 20057358, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    Synthetic with Lin-35/Rb
    NP_001256772.1
    • Product from WormBase gene class slr;
      Confirmed by transcript evidence
    NP_001256773.1
    • Product from WormBase gene class slr;
      Confirmed by transcript evidence
    NP_001256774.1
    • Product from WormBase gene class slr;
      Confirmed by transcript evidence
    NP_001256775.1
    • Product from WormBase gene class slr;
      Confirmed by transcript evidence
    NP_001256776.1
    • Product from WormBase gene class slr;
      Confirmed by transcript evidence
    NP_001256777.1
    • Product from WormBase gene class slr;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      18087123..18098118
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269843.4 → NP_001256772.1  Synthetic with Lin-35/Rb [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256772.1

      Status: REVIEWED

      Conserved Domains (1) summary
      sd00017
      Location:48 → 68
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. NM_001269844.3 → NP_001256773.1  Synthetic with Lin-35/Rb [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256773.1

      Status: REVIEWED

      Conserved Domains (1) summary
      sd00017
      Location:48 → 68
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. NM_001269845.1 → NP_001256774.1  Synthetic with Lin-35/Rb [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256774.1

      Status: REVIEWED

      Conserved Domains (1) summary
      sd00017
      Location:48 → 68
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. NM_001269846.1 → NP_001256775.1  Synthetic with Lin-35/Rb [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256775.1

      Status: REVIEWED

      Conserved Domains (1) summary
      sd00017
      Location:48 → 68
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. NM_001269847.3 → NP_001256776.1  Synthetic with Lin-35/Rb [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256776.1

      Status: REVIEWED

    6. NM_001269848.1 → NP_001256777.1  Synthetic with Lin-35/Rb [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256777.1

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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