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    W03D8.8 BAAT/acyl-CoA thioester hydrolase protein [ Caenorhabditis elegans ]

    Gene ID: 189157, updated on 9-Dec-2024

    Summary

    Official Symbol
    W03D8.8
    Official Full Name
    BAAT/acyl-CoA thioester hydrolase protein
    Primary source
    WormBase:WBGene00020989
    Locus tag
    CELE_W03D8.8
    See related
    AllianceGenome:WB:WBGene00020989
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Human ortholog(s) of this gene implicated in disease of metabolism. Orthologous to several human genes including ACOT1 (acyl-CoA thioesterase 1); ACOT2 (acyl-CoA thioesterase 2); and ACOT4 (acyl-CoA thioesterase 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See W03D8.8 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (2791687..2794976)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein Neighboring gene BTB domain-containing protein Neighboring gene Serine/threonine-protein phosphatase Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty acyl-CoA hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables thiolester hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in acyl-CoA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in acyl-CoA metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    BAAT/acyl-CoA thioester hydrolase protein
    NP_491047.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      2791687..2794976
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058646.3NP_491047.2  BAAT/acyl-CoA thioester hydrolase protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491047.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45003
      Conserved Domains (2) summary
      pfam04775
      Location:14130
      Bile_Hydr_Trans; Acyl-CoA thioester hydrolase/BAAT N-terminal region
      pfam08840
      Location:196408
      BAAT_C; BAAT / Acyl-CoA thioester hydrolase C terminal