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    samp-1 Transmembrane protein 201 homolog [ Caenorhabditis elegans ]

    Gene ID: 174727, updated on 2-Nov-2024

    Summary

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    Official Symbol
    samp-1
    Official Full Name
    Transmembrane protein 201 homolog
    Primary source
    WormBase:WBGene00011994
    Locus tag
    CELE_T24F1.2
    See related
    AllianceGenome:WB:WBGene00011994
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin filament binding activity and lamin binding activity. Involved in embryo development and nuclear migration along microtubule. Located in nuclear envelope. Orthologous to human TMEM201 (transmembrane protein 201). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See samp-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    7
    Sequence:
    Chromosome: II; NC_003280.10 (11302891..11305626)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serine/threonine-protein phosphatase 6 regulatory subunit Neighboring gene GTP-binding protein Neighboring gene Ras association domain-containing protein 1 homolog Neighboring gene ncRNA Neighboring gene Small integral membrane protein 36 Neighboring gene EGF-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration. Bone CR, et al. Mol Biol Cell, 2014 Sep 15. PMID 25057012, Free PMC Article
    2. Predictive models of molecular machines involved in Caenorhabditis elegans early embryogenesis. Gunsalus KC, et al. Nature, 2005 Aug 11. PMID 16094371
    3. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    4. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    5. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lamin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in embryo development ending in birth or egg hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear migration along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in nuclear migration along microtubule IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Transmembrane protein 201 homolog
    NP_496416.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      11302891..11305626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064015.7 → NP_496416.1  Transmembrane protein 201 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496416.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22747
      Conserved Domains (1) summary
      pfam09779
      Location:29 → 158
      Ima1_N; Ima1 N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q22747.1

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