mau-2 Maternal uncoordinated protein 2 [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: mau-2
Official Full Name: Maternal uncoordinated protein 2
Primary source: WormBase:WBGene00003136
Locus tag: CELE_C09H6.3
See related: AllianceGenome:WB:WBGene00003136
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable double-stranded DNA binding activity. Involved in anterior/posterior axon guidance; dorsal/ventral axon guidance; and egg-laying behavior. Located in axon and cytoplasm. Is expressed in nervous system; oocyte; and vulval muscle. Orthologous to human MAU2 (MAU2 sister chromatid cohesion factor). [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See mau-2 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 9

Sequence:: Chromosome: I; NC_003279.8 (8125801..8130039)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

mau-2 defines a novel guidance factor that might be involved in the intracellular processing of guidance cues encountered by migrating cells and axons during development
Title: mau-2 acts cell-autonomously to guide axonal migrations in Caenorhabditis elegans.

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

C09H6.3 (e-PCR)
- UniSTS:313525

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables double-stranded DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in anterior/posterior axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in cell cycle	IEA Inferred from Electronic Annotation more info
involved_in cell division	IEA Inferred from Electronic Annotation more info
involved_in chromosome segregation	IEA Inferred from Electronic Annotation more info
involved_in dorsal/ventral axon guidance	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in egg-laying behavior	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in maintenance of mitotic sister chromatid cohesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in maintenance of mitotic sister chromatid cohesion	ISS Inferred from Sequence or Structural Similarity more info
involved_in mitotic sister chromatid cohesion	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SMC loading complex	IBA Inferred from Biological aspect of Ancestor more info
part_of SMC loading complex	ISS Inferred from Sequence or Structural Similarity more info
located_in axon	IDA Inferred from Direct Assay more info	PubMed
located_in chromatin	IBA Inferred from Biological aspect of Ancestor more info
located_in chromatin	ISS Inferred from Sequence or Structural Similarity more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: Maternal uncoordinated protein 2

NP_492228.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

8125801..8130039

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059827.7 → NP_492228.1 Maternal uncoordinated protein 2 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492228.1

Status: REVIEWED

UniProtKB/Swiss-Prot

O17581

Conserved Domains (1) summary

pfam10345
Location:25 → 419

Cohesin_load; Cohesin loading factor