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    set-30 MYND-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180772, updated on 9-Dec-2024

    Summary

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    Official Symbol
    set-30
    Official Full Name
    MYND-type domain-containing protein
    Primary source
    WormBase:WBGene00022499
    Locus tag
    CELE_ZC8.3
    See related
    AllianceGenome:WB:WBGene00022499
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables histone H3K4 methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be active in nucleus. Is expressed in muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See set-30 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Sequence:
    Chromosome: X; NC_003284.9 (4999270..5003516)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Phosphatidylinositol 4-kinase type 2 Neighboring gene ncRNA Neighboring gene Rootletin-like coiled-coil domain-containing protein Neighboring gene ncRNA Neighboring gene 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein Neighboring gene 3-beta hydroxysteroid dehydrogenase/isomerase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Epigenetic effects induced by silver nanoparticles in Caenorhabditis elegans after multigenerational exposure. Wamucho A, et al. Sci Total Environ, 2020 Jul 10. PMID 32305644, Free PMC Article
    2. Mutation of C. elegans demethylase spr-5 extends transgenerational longevity. Greer EL, et al. Cell Res, 2016 Feb. PMID 26691751, Free PMC Article
    3. Genome-wide functional analysis of CREB/long-term memory-dependent transcription reveals distinct basal and memory gene expression programs. Lakhina V, et al. Neuron, 2015 Jan 21. PMID 25611510, Free PMC Article
    4. A histone methylation network regulates transgenerational epigenetic memory in C. elegans. Greer EL, et al. Cell Rep, 2014 Apr 10. PMID 24685137, Free PMC Article
    5. Regulators of H3K4 methylation mutated in neurodevelopmental disorders control axon guidance in Caenorhabditis elegans. Abay-Nørgaard S, et al. Development, 2020 Aug 7. PMID 32675280, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables histone H3K4 methyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin remodeling IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MYND-type domain-containing protein
    NP_508850.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4999270..5003516
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076449.6 → NP_508850.2  MYND-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508850.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q23084
      Conserved Domains (2) summary
      pfam01753
      Location:41 → 78
      zf-MYND; MYND finger
      cd20071
      Location:179 → 266
      SET_SMYD; SET domain (including SET domain and post-SET domain) found in SET and MYND domain-containing protein, and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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