U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    cox-11 Cytochrome c oxidase assembly protein COX11, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 186814, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    cox-11
    Official Full Name
    Cytochrome c oxidase assembly protein COX11, mitochondrial
    Primary source
    WormBase:WBGene00010437
    Locus tag
    CELE_JC8.5
    See related
    AllianceGenome:WB:WBGene00010437
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable copper ion binding activity. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Is expressed in intestine and nervous system. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 23. Orthologous to human COX11 (cytochrome c oxidase copper chaperone COX11). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See cox-11 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (13244324..13247160)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene CRC domain-containing protein;Protein lin-54 Neighboring gene CMP/dCMP-type deaminase domain-containing protein Neighboring gene Zinc finger, CCHC-type Neighboring gene Transthyretin-like family protein Neighboring gene Transthyretin-like family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Cytochrome c oxidase assembly protein COX11, mitochondrial
    NP_001293852.1
    • Confirmed by transcript evidence
    NP_502547.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      13244324..13247160
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_070146.7 → NP_502547.2  Cytochrome c oxidase assembly protein COX11, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502547.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95QD5
      Conserved Domains (1) summary
      pfam04442
      Location:79 → 229
      CtaG_Cox11; Cytochrome c oxidase assembly protein CtaG/Cox11

    2. NM_001306923.3 → NP_001293852.1  Cytochrome c oxidase assembly protein COX11, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001293852.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      S6F574
      Conserved Domains (1) summary
      pfam04442
      Location:14 → 164
      CtaG_Cox11; Cytochrome c oxidase assembly protein CtaG/Cox11
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous